Parkinson’s Disease (PD)
Parkinson’s disease is a nervous system disorder. It’s a progressive disease; symptoms will continue to worsen as time passes.
In early stages, symptoms mainly affect the way a person moves. But cognitive changes can occur in more advanced stages.
According to the Parkinson’s Foundation, almost one million people in the U.S. are living with the disease.
Parkinson’s disease is not curable, but there are many effective treatments to help manage the disease.
Who Gets Parkinson’s Disease?
Parkinson’s disease usually appears at age 60 or older. But people under 50 can also be diagnosed withearlyonset Parkinson’s disease.
Parkinson’s disease is more prevalent in men than women. The risk seems to increase for women as they age.
Toxin exposure and past traumatic brain injury may increase the risk of developing Parkinson’s disease. A family history of the disease may slightly increase the risk as well.
What Causes Parkinson’s Disease?
When a person has this disease, nerve cells in the brain break down or die.
The neurons no longer produce adequate amounts of dopamine—a critical brain chemical needed for normal brain activity. This chemical shortage affects certain areas of the brain. The results are limited movements and other symptoms.
A second neurotransmitter, norepinephrine, also becomes limited. This brain chemical helps the sympathetic nervous system work properly. Functions such as heart rate, blood pressure and breathing are all regulated by the sympathetic nervous system. Many of the non-movement symptoms of Parkinson’sresult from limited amounts of norepinephrine.
It remains a mystery why these chemical imbalances occur in the brain.
Research shows that contributing factors may include specific gene mutations and markers and exposure to certain environmental factors, especially some herbicides and pesticides.
But even these factors aren’t considered major causes of Parkinson’s disease.
Symptoms of Parkinson's Disease
Early stage symptoms
PD symptoms often appear slowly, and they can be quite mild. Sometimes they’re not even noticed until someone close to the patient points them out.
The severity of symptoms among PD sufferers varies. There isn’t an organized way that symptoms develop. And not every patient exhibits every symptom.
Early symptoms usually occur on one side of your body. Eventually, these symptoms will affect both sides.
Early stage Parkinson’s disease symptoms can include:
Disease symptoms become more obvious and troublesome. Symptoms that initially started on one side of the body now affect both sides.
The patient may stumble or fall more frequently. While they still function independently, motor tasks become more difficult. Everyday chores, such as getting dressed or showering, start to take longer.
Tremors are slightly more noticeable and usually disappear when there is movement, or during sleep.
More advanced symptoms of Parkinson’s disease may include:
There is a loss of automatic body movements, including smiling or blinking. Changes in speech, including slurring of words or hesitation speaking begin to occur frequently.
As Parkinson’s disease progresses and stages advance, a person can develop serious cognitive problems and more worrisome physical limitations.
It is common for patients to need assistance with everyday tasks.
Often patients need a walker to move around. It’s difficult, if not impossible, for patients to live at home without live-in help.
Symptoms of mid-late stage Parkinson’s disease can include:
Advanced stage disease
At this point, patients have extreme physical limitations. They will have serious issues with posture and will need a wheelchair to move around.
Many patients become incontinent, and some are completely bedridden.
It’s not uncommon for patients to suffer hallucinations or delusions, sometimes brought on by medication.
Full-time nursing care is a must.
Parkinson’s Disease Treatment
Medications help most patients maintain a good quality of life and are the primary method of treatment.
Some medications work to restore the proper balance of dopamine and other neurotransmitters in the brain. This reduces symptoms.
Doctors may prescribe medication to help with emotional problems and sleep disturbances. If treatment with medication doesn’t work, surgery may improve symptoms.
Some patients are excellent candidates for a deep brain stimulator (DBS). During surgery, surgeons implant electrodes in the brain. They create electrical impulses that correct abnormal brain activity. This treatment effectively eases motor symptoms, but it can’t improve cognitive problems.
Physical, speech, and other therapies are effective in helping with balance, walking, eating and speech problems.
Since researchers know little about the causes of Parkinson’s disease, there is no known way to prevent it. However, research continues in the ongoing fight against this debilitating disease.
Medications and therapies can help reduce and manage symptoms to maintain a good quality of life.